Greyhound regimen; applicability to other sighthounds is less established.
Sighthound bacterial infection
9 mg/kg
SC, IM
Every 24 h
Greyhound regimen; applicability to other sighthounds is less established.
Cat
Use / stage
Dose
Route
Schedule
Instructions
Bacterial infection
5–8 mg/kg
SC, IM, IV
Every 24 h
Do not use in: Renal insufficiency
Horse
Use / stage
Dose
Route
Schedule
Instructions
Adult bacterial infection
4–6.6 mg/kg
IM, IV
Every 24 h
Do not use in: Renal insufficiency
Neonatal foal infection
12–14 mg/kg
IM, IV
Every 24 h
Do not use in: Renal insufficiency; Foals younger than 2 weeks.
Pig
Use / stage
Dose
Route
Schedule
Instructions
Young-pig bacterial infection
15 mg/kg
SC, IM
Every 24 h
Do not use in: Renal insufficiency
Older-pig bacterial infection
10 mg/kg
SC, IM
Every 24 h
Do not use in: Renal insufficiency
Enteric infection
Reference only
PO
Do not use in: Renal insufficiency; 1.1–2.2 mg/kg in drinking water for 3 days; source does not clearly define dose frequency or water-intake assumptions.
Medicated-water colibacillosis treatment
Reference only
PO
1.1 mg/kg/day in drinking water for three days; the source gives 25 mg per gallon. Consumption-dependent dosing must be reconciled with body weight and actual water intake.
Medicated-water dysentery treatment
Reference only
PO
2.2 mg/kg/day in drinking water for three days; the source gives 50 mg per gallon. Water-intake-based medication cannot be flattened into a bolus dose.
Cattle
Use / stage
Dose
Route
Schedule
Instructions
Neonatal calf infection
12–15 mg/kg
IV, IM
Every 24 h
Do not use in: Renal insufficiency; Calves younger than 2 weeks; prolonged residue concerns.
Adult bacterial infection
5–6 mg/kg
IM, IV
Every 24 h
Do not use in: Renal insufficiency
Chinchilla
Use / stage
Dose
Route
Schedule
Instructions
Susceptible bacterial infection
2–4 mg/kg
SC, IM
Every 8–24 h
Maintain hydration; monitor for nephrotoxicity and ototoxicity.
Gerbil
Use / stage
Dose
Route
Schedule
Instructions
Susceptible bacterial infection
2–4 mg/kg
SC, IM
Every 8–24 h
Maintain hydration; monitor for nephrotoxicity and ototoxicity.
Guinea Pig
Use / stage
Dose
Route
Schedule
Instructions
Susceptible bacterial infection
2–4 mg/kg
SC, IM
Every 8–24 h
Maintain hydration; monitor for nephrotoxicity and ototoxicity.
Hamster
Use / stage
Dose
Route
Schedule
Instructions
Susceptible bacterial infection
2–4 mg/kg
SC, IM
Every 8–24 h
Maintain hydration; monitor for nephrotoxicity and ototoxicity.
Mouse
Use / stage
Dose
Route
Schedule
Instructions
Susceptible bacterial infection
2–4 mg/kg
SC, IM
Every 8–24 h
Maintain hydration; monitor for nephrotoxicity and ototoxicity.
Rat
Use / stage
Dose
Route
Schedule
Instructions
Susceptible bacterial infection
2–4 mg/kg
SC, IM
Every 8–24 h
Maintain hydration; monitor for nephrotoxicity and ototoxicity.
Ferret
Use / stage
Dose
Route
Schedule
Instructions
Susceptible bacterial infection
5 mg/kg
SC, IM
Every 24 h
Use only when susceptibility and clinical need justify the nephrotoxicity risk.
Rabbit
Use / stage
Dose
Route
Schedule
Instructions
Susceptible bacterial infection
5–8 mg/kg
SC, IM, IV
Every 24 h
For IV use, the described regimen dilutes into 4 mL/kg saline and infuses over 20 minutes. Monitor renal function.
Ratite
Use / stage
Dose
Route
Schedule
Instructions
Susceptible bacterial infection
5 mg/kg
IM
Every 24 h
Last-resort option because visceral gout can occur.
Monitor renal parameters, urinalysis and drug concentrations where available. Once-daily trough should be very low; impaired clearance requires reassessment.
Food-animal systemic use can leave very prolonged renal residues; do not apply short oral-product withdrawal times to injections.
