Inspired concentration approximately 3%, titrated to effect. Percent vapour concentration is not a body-weight dose.
Anaesthetic maintenance — Maintenance
Reference only
INHALATION
Inspired concentration 0.5-1.5%, titrated to depth.
Alternative anaesthetic concentration
Reference only
INHALATION
0.5-3.5% inhaled, titrated to depth and fresh-gas flow.
Cats
Use / stage
Dose
Route
Schedule
Instructions
Anaesthetic induction — Initial
Reference only
INHALATION
Inspired concentration approximately 3%, titrated to effect. Percent vapour concentration is not a body-weight dose.
Anaesthetic maintenance — Maintenance
Reference only
INHALATION
Inspired concentration 0.5-1.5%, titrated to depth.
Alternative anaesthetic concentration
Reference only
INHALATION
0.5-3.5% inhaled, titrated to depth and fresh-gas flow.
Horses
Use / stage
Dose
Route
Schedule
Instructions
Anaesthetic requirement
Reference only
INHALATION
Large-animal MAC approximately 1%; MAC is a potency measure rather than a fixed vaporizer prescription.
Draft-horse anaesthesia
Reference only
INHALATION
After induction and intubation, initial 4-5% in an oxygen-enriched semi-closed circuit; reduce promptly to effect. Draft-horse maintenance described at 2.5-3%, using the lowest effective concentration.
Mice
Use / stage
Dose
Route
Schedule
Instructions
General anaesthesia
Reference only
INHALATION
Non-rebreathing circuit: induction 2-4%, maintenance 0.25-2%; adjust to ventilation and anaesthetic depth.
Rats
Use / stage
Dose
Route
Schedule
Instructions
General anaesthesia
Reference only
INHALATION
Non-rebreathing circuit: induction 2-4%, maintenance 0.25-2%; adjust to ventilation and anaesthetic depth.
Gerbils
Use / stage
Dose
Route
Schedule
Instructions
General anaesthesia
Reference only
INHALATION
Non-rebreathing circuit: induction 2-4%, maintenance 0.25-2%; adjust to ventilation and anaesthetic depth.
Hamsters
Use / stage
Dose
Route
Schedule
Instructions
General anaesthesia
Reference only
INHALATION
Non-rebreathing circuit: induction 2-4%, maintenance 0.25-2%; adjust to ventilation and anaesthetic depth.
Guinea pigs
Use / stage
Dose
Route
Schedule
Instructions
General anaesthesia
Reference only
INHALATION
Non-rebreathing circuit: induction 2-4%, maintenance 0.25-2%; adjust to ventilation and anaesthetic depth.
Chinchillas
Use / stage
Dose
Route
Schedule
Instructions
General anaesthesia
Reference only
INHALATION
Non-rebreathing circuit: induction 2-4%, maintenance 0.25-2%; adjust to ventilation and anaesthetic depth.
Birds
Use / stage
Dose
Route
Schedule
Instructions
General anaesthesia
Reference only
INHALATION
Small birds: induction around 2%; large birds 2.5-3%. Maintenance 0.5-1.5%. Watch for bradycardia, hypotension and hypothermia.
Succinylcholine may trigger malignant hyperthermia; aminoglycosides, lincosamides and neuromuscular blockers may increase paralysis. Avoid postoperative paracetamol after halothane exposure.
Excess inhaled concentration can cause severe cardiorespiratory depression. Reduce or stop delivery and support oxygenation, ventilation and circulation.
Use a calibrated vaporizer, oxygen delivery and waste-gas scavenging.
Monitor anaesthetic depth, ventilation, heart rate and rhythm, blood pressure and temperature.
Keep the volatile liquid tightly sealed. MAC values are approximately 1.04% in cats, 0.87% in dogs and 0.88% in horses.
Halothane is supplied as volatile liquid in a 250 mL bottle.
Store below 40°C in a light-resistant container. Discard discoloured liquid; thymol can accumulate in the vaporizer. Moist halothane can react with certain metals and damage rubber or plastics.
