Alternative surgical-pain regimen; use a product suitable for the selected route.
Pain and inflammation
2.2 mg/kg
PO
Every 12–24 h
Cats
Use / stage
Dose
Route
Schedule
Instructions
Perioperative analgesia
Reference only
PO
4 mg/kg once by injection. The dosage passage does not specify an injection route; no route is inferred.
Long-term analgesia
0.5 mg/kg
PO
Every 24 h
Pharmacokinetic extrapolation only; long-term feline safety is not established.
Perioperative analgesia
1–4 mg/kg
SC
Once
Pre- or postoperative single-dose alternative; 1–2 mg/kg has been described with similar efficacy and greater safety. Do not extrapolate to repeated canine dosing.
Short-course analgesia
2 mg/kg
PO
Every 12 h
Up to 2 days; Historical feline oral regimen, limited to two days. This is not evidence for long-term safety.
Lower-dose short-course analgesia
Reference only
PO
Less than 1 mg/kg orally once daily for 2–3 treatments; the open-ended less-than limit is not encoded as an invented numeric range.
Horses
Use / stage
Dose
Route
Schedule
Instructions
Pain and inflammation
0.7 mg/kg
IV
Every 24 h
Pain and inflammation
0.7 mg/kg
PO
Oral granules are described; the oral interval is not explicitly stated in that alternative.
Acute pain and inflammation
0.7 mg/kg
IV
Once
Cattle
Use / stage
Dose
Route
Schedule
Instructions
Inflammation
1.4 mg/kg
SC, IV
Escherichia coli mastitis-associated inflammation
0.7 mg/kg
IV
Dose described in the clinical-use discussion.
Rabbits
Use / stage
Dose
Route
Schedule
Instructions
Chronic joint pain
2.2 mg/kg
PO
Every 12 h
Rats
Use / stage
Dose
Route
Schedule
Instructions
Analgesia
5 mg/kg
SC
Analgesia
5–10 mg/kg
PO
Chinchillas
Use / stage
Dose
Route
Schedule
Instructions
Analgesia
4 mg/kg
SC
Every 24 h
Birds
Use / stage
Dose
Route
Schedule
Instructions
Pain and inflammation
2 mg/kg
PO
Every 8–24 h
Chickens
Use / stage
Dose
Route
Schedule
Instructions
Lameness-associated pain
1 mg/kg
SC
Reptiles
Use / stage
Dose
Route
Schedule
Instructions
Pain and inflammation
1–4 mg/kg
IV, IM, SC, PO
Every 24–72 h
Broad historical reptile recommendation; individual species evidence and hydration must guide use.
Check hepatic enzymes about 7–14 days after starting and reassess if appetite, stool or activity changes.
A compounded oral suspension made using methylcellulose, syrup and a suitable vehicle has reported stability for 28 days refrigerated or at room temperature.
Cattle have prolonged elimination; withdrawal decisions are formulation- and jurisdiction-specific.
Baseline assessment for prolonged therapy includes examination, CBC, chemistry and urinalysis. Recheck liver enzymes at approximately 1, 2 and 4 weeks, then at 3–6-month intervals if stable.
For the described canine injectable product, refrigerate unopened at 2–8°C; after first use it may be held at up to 25°C for 28 days. Do not apply tablet room-temperature storage to injection.
Two compounded vehicles have different stability: the previously described methylcellulose formulation had 28-day data; 100 mg tablet in Ora-Plus/Ora-Sweet to final 20 mL gives 5 mg/mL with 21-day potency at 5°C or 25°C, protected from light.
