Erythropoiesis in Animals From stem cell, the formation of reticulocyte takes about 72 hours and conversion of reticulocyte to erythrocyte requires 48 hours. Thus RBC formation requires 5 days time. Under appropriate stimulation, CFU-E progenitor cells produce proerythroblast. Hb synthesis begins in polychromatophil erythroblast and maximum synthesis occurs in orthochromatic erythroblast. The metarubricyte ejects the […]

Life span and Hemolysis of RBCs in animals Life span of erythrocytes Cattle Sheep Goat Horse Dog Cat Pig Poultry 125-150 140-150 125-150 140-150 100-120 70-80 51-79 20-30 Life span of erythrocytes (days) Site of destruction of erythrocytes In most of the domestic animals bone marrow functions as a chief site of destruction of erythrocytes,

Erythrocytic indices in animals Erythrocytic indices in animals help in the diagnosis various types of anemia (microcytic vs. macrocytic or normocytic). Mean Corpuscular Volume (MCV) Mean Corpuscular Volume expresses the average cell size of the erythrocyte. Mean Corpuscular Hemoglobin (MCH) Mean Corpuscular Hemoglobin gives the average weight of Hb present in the erythrocytes. Mean Corpuscular

Abnormalities of RBC Concentration in animals Abnormalities of RBC Concentration in animals are Polycythemia, Oligocythemia and Anemia. Polycythemia in Animals It is otherwise known as erythrocytosis. It is a condition of increased number of RBCs in the circulation. It is of two types. Physiological (secondary) polycythemia An increase in RBCs occurs as a compensatory measure (in high

Erythrocyte/RBC of Animals Functions of erythrocytes Transport hemoglobin which in turn carries oxygen from the lungs to the tissues. RBCs contain large quantity of carbonic anhydrase which catalyzes the reversible reaction between carbon dioxide and water. Thereby makes it possible for the water of the blood to transport enormous quantities of carbon dioxide from the

Plasma Lipids Lipids are heterogenous molecules soluble in organic solvents but not in water. They are esters of fatty acids, formed by the reaction of  fatty acids with glycerol. Blood lipids (or blood fats) are lipids in the blood and they are present either free or bound to other molecules. Blood lipids are mainly fatty acids, triglycerides,

Plasma Proteins of blood in animals Plasma proteins of blood in animals contribute about 7% of the total organic molecules of the plasma. The major proteins present in plasma are- Albumin (55%), Globulins (38 %) and Fibrinogen (7 %). Liver functions as a chief site of synthesis of plasma proteins, albumin, fibrinogen, prothrombin and some of the

Viscosity and pH of Blood of Animals Viscosity and pH of Blood of Animals is described below: Viscosity of Blood of Animals Viscosity is influenced by concentration of RBCs and plasma proteins. Among plasma proteins, the viscosity is mainly contributed by the gamma globulins which provide the resistance to blood flow and helps the normal pumping activity

Specific Gravity of Blood Specific gravity is the ratio of weight of a given volume of a fluid to the weight of the same volume of distilled water measured at 25°C. Plasma protein concentration is largely responsible for the specific gravity of the plasma. The cellular elements called the corpuscles have higher specific gravity than