Connective tissue of peripheral nerve

A cross section of a peripheral nerve shows that it is surrounded by a sheath of loose connective tissue called epineurium inside this wrapping several bundles of nerve fibres are seen and each of these is surrounded by a dense connective tissue sheath called perineurium. Inside these bundles are the nerve fibres.

Each nerve fibre is surrounded by a tube of delicate connective tissue fibrils. These tubes are endoneurial tubes or sheath of Henle. Endoneurium is adherent to neurolemma.

Each bundle of nerve fibres surrounded by perineurium is called a fascicle.

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