Toxicity of Drugs

Toxicity of Drugs is seen when indiscriminate or medicine given in higher dose. some drugs that have very low therapeutic index like vincristine, these drug harmful even little high dose. and some drugs like Pantoprazole have wide therapeutic index so higher dose also safe.

Body Size, Age, Sex, Species, Race, diet, plane of nutrition, genetics, route of administration, environmental and physiological factors, disease status, enzymes are some factors that also effect on drugs functions. Read more on “Factors that affects drug action“.