Pro-opiomelanocortin

Veterinary Physiology

Pro-opiomelanocortin Within the pituitary gland, ACTH is produced in a process that also generates several other hormones. A large precursor protein named pro -opiomelanocortin (POMC) is synthesized in the intermediate lobe and in the corticotropes of anterior pituitary and proteolytically chopped into several fragments. Not all of the cleavages occur in all species and some occur only

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Adrenocorticotropic hormone (ACTH)

Veterinary Physiology

Adrenocorticotropic hormone (ACTH) Adrenocorticotropic hormone (ACTH) is a polypeptide containing 39 amino acids in a straight chain in sheep, pig, cow and man. It stimu­lates synthesis and immediate release of corticosteroids. It helps the uptake of cholesterol by the adrenal cells, choles­terol ester hydrolysis, cholesterol transfer to mitochondria, the rate‑limiting desmolase reaction and the critical

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