Distribution of cholinergic and adrenergic neurons

Veterinary Pharmacology

Predominant Sympathetic or Parasympathetic Tone in various structures Site Predominant Tone  Arterioles  Sympathetic (Adrenergic)  Veins  Sympathetic (Adrenergic)  Heart: atrium SA node Ventricle  Parasympathetic (Cholinergic) Parasympathetic (Cholinergic) Sympathetic (Adrenergic)  Iris  Parasympathetic (Cholinergic)  Ciliary Muscle  Parasympathetic (Cholinergic)  G.I. Tract  Parasympathetic (Cholinergic)  Urinary Bladder  Parasympathetic (Cholinergic)  Salivary Gland  Parasympathetic (Cholinergic)  Sweat Glands  Sympathetic (Adrenergic) In organs receiving both sympathetic and parasympathetic innervations […]

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Basics of Autonomic nerve system in pharmacology

Veterinary Pharmacology

Autonomic nerve system The autonomic nervous system is also known as the visceral, vegetative or involuntary nervous system widely distributed throughout the body controlling the so called autonomic or vegetative functions. The ANS regulates activity of structures like the smooth muscles, cardiac muscle and secretory glands other than endocrine glands. The ANS is responsible for maintaining respiration,

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Ecbolics and Tocolytics

Veterinary Pharmacology

Ecbolic drugs Ecbolic drugs are agents that bring about increase in uterine contractions. Oxytocin: It is hormone of the posterior pituitary received from the hypothalamus. It has a major physiological role in milk let down and labor initiation. Clinical uses of oxytocin: For labor induction. Given by slow I/v in dextrose solution. For mIlk letdown

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Urine Alkalizers

Veterinary Pharmacology

Urine Alkalizers Urine Alkalizers are used to increase pH of urine. these used as a test for renal tubular acidosis. Acidification helps in the excretion of certain drugs like amphetamine, phencyclidine, quinine etc. Ammonium chloride, ascorbic acid or calcium chloride can be used to acidify urine. Ammonium chloride (NH4Cl) is metabolized in the liver to

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Urine acidifiers

Veterinary Pharmacology

Urine acidifiers Urinary acidifiers used to decrease pH of urine (Acidifiers make urine acidic). Alteration of urine pH Alteration is sometimes desirable as in the case of poisoning and in the excretion of some drugs to prevent side effects. Alkalization of urine Alkalinising agents reduce the irritation of an inflamed urinary tract and discourage the growth

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Diuretic drugs

Veterinary Pharmacology

Diuretics Diuretic drugs are agents that increase the salt and water excretion by an action on the kidneys. Diuretics effective for the treatment of edema have been available since the 16th century and mercurous chloride was known by Paracelsus to be diuretic. In 1930, Swartz discovered that the antimicrobial sulfanilamide could be used to treat edema

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Anticoagulant drugs

Veterinary Pharmacology

Anticoagulants Anticoagulants are agents that inhibit coagulation of blood either in vitro or in vivo. The in vitro anticoagulants are useful in the collection of blood for laboratory analysis or for blood transfusion. In vitro anticoagulants In vivo anticoagulants Heparin is used as Systemic anticoagulants or In vivo type anticoagulant. here are some features of heparin listed below- Clinical uses

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Epistaxis in a dog (bleeding from nose) - Classification of Haemorrhage, Coagulants should be used to stop bleeding or causative agent should be removed.

Coagulants

Veterinary Pharmacology

Coagulant drugs Coagulants are agents that promote coagulation of blood. Various coagulants used are Thromboplastin, Thrombin, Fibrinogen, Fibrin, Oxidized cellulose, Calcium alginate, and Absorbable gelatin sponge. Coagulant drugs used in animals listed as- Thromboplastin Thromboplastin (thrombokinase) is produced naturally by platelets and damaged tissue. Commercial thromboplastin is an extract of cattle brain in normal saline.

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Hematinic drugs

Veterinary Pharmacology

Hematinics Hematinics are agents or drugs which are used in the treatment of anaemia and generally act by stimulation of hemoglobin synthesis of erythropoiesis. Iron Iron is necessary for hamoglobin formation. It is available in the diet. However often it is supplemented for the treatment of deficiency of iron  by giving as oral or parenteral

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